Postpartum Support Charleston hosts its largest annual fundraiser, the 21st-annual Moms’ Run. Participants will start at Philip Simmons High School before making a loop on foot, completing a 5K or one-mile route. The race benefits Lowcountry women experiencing postpartum mood disorders such as depression, anxiety, and OCD. Philip Simmons High School, 3080 River Village Dr., Wando. Saturday, 8:30am. $30-$15. (843)410-3585, www.ppdsupport.org