Don’t worry about changing out of your nighty for this year’s Pajama Run 5K. Proceeds from the event benefit the Hollings Cancer Center at MUSC, which focuses on cancer prevention programs through quality care, research, and professional education. Celebrate during the after party with food, drinks, and awards given to the winners in each age category, the person with the best pajama outfit, and the individual or group who raises the most money. Race starts at 10 a.m. Joseph P. Riley, Jr. Park, 360 Fishburne St. Saturday, 9-11am. $35; $25 advance. (843)225-1012, www.pajamarun.com